| 王伟业,郭萍,姚昭,高杨.孕早期睡眠时长与午睡频次对妊娠糖尿病的影响[J].井冈山大学自然版,2021,42(1):96-100 |
| 孕早期睡眠时长与午睡频次对妊娠糖尿病的影响 |
| EFFECT OF SLEEP DURATION AND MIDDAY NAPPING FREQUENCY IN EARLY PREGNANCY ON GESTATIONAL DIABETES MELLITUS |
| 投稿时间：2020-09-08 修订日期：2020-11-16 |
| DOI：10.3969/j.issn.1674-8085.2021.01.016 |
| 中文关键词: 妊娠糖尿病 睡眠时长 午睡 交互作用 |
| 英文关键词: gestational diabetes mellitus sleep duration midday napping interaction |
| 基金项目:江西省教育厅科学技术计划项目（GJJ170647）；井冈山大学博士科研启动项目（JZB1817） |
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| 中文摘要: |
| 目的 探讨孕早期睡眠时长和午睡频次对妊娠糖尿病（GDM）的影响。方法 采用病例对照研究设计，选取2018年4月至2019年5月在安徽省妇幼保健院、吉安市妇幼保健院产检的孕妇作为研究对象。通过问卷调查收集研究对象的睡眠和午睡等信息，GDM的诊断来自孕中期常规口服葡萄糖耐量试验结果。结果 共纳入500名研究对象，其中病例组196人，对照组304人。多元Logistic回归分析结果显示，与睡眠时长7~8.9 h/晚相比，睡眠<7、9~9.9、≥10 h/晚的孕妇发生GDM的风险均显著上升；与午睡频次≤5 d/周相比，>5 d/周的孕妇发生GDM的风险更高。相比孕早期午睡频率 ≤ 5 d/周的孕妇，孕早期睡眠时长不足（< 7 h/晚）对GDM的影响在午睡频率>5 d/周的孕妇中更弱，交互作用具有统计学意义（P=0.002）。结论 孕早期睡眠时长、午睡频次均与GDM发病相关，且二者在GDM的发生中存在交互作用。 |
| 英文摘要: |
| Objective: To explore the effects of sleep duration and midday napping frequency in early pregnancy on gestational diabetes mellitus (GDM). Methods: In this case-control study, taking pregnancy women who attended antenatal visit in Anhui Maternal and Child Health Hospital and Ji’an Maternal and Child Health Hospital from April 2018 to May 2019 as study subjects. Information of midday napping and sleep duration were assessed by a semi-quantitative questionnaire, the diagnostic information of GDM was derived from the routine oral glucose tolerance test during their second pregnancy trimester. Results: A total of 500 pregnancy women including 196 GDM patients and 304 controls were taken into the present study. Compared with the sleep duration of 7-8.9 hours/night, pregnant women whose sleep was less than 7, 9-9.9 or greater than or equal to 10 hours/night all had significantly increased risk of GDM. Compared with napping frequency less than or equal to 5 days/week, pregnant women with >5 days/week had a higher risk of GDM. Compared with women whose napping frequency was ≤5 days/week in early pregnancy, the effect of insufficient sleep duration (<7 hours/night) on GDM was weaker in pregnant women whose napping frequency was >5 days/week, and the interaction was statistically significant (P=0.002). Conclusion: Sleep duration and midday napping frequency in early pregnancy were both correlated with GDM, and they had an interaction effect on the occurrence of GDM. |
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