| 王晓刚,李红,张连凤,万颖超,刘晓琼,欧阳爱军.布洛芬诱发1例危重阿司匹林哮喘临床分析[J].井冈山大学自然版,2017,(6):98-101 |
| 布洛芬诱发1例危重阿司匹林哮喘临床分析 |
| CLINICAL ANALYSIS OF 1 CASE OF SEVERE ASPIRIN ASTHMA INDUCED BY IBUPROFEN |
| 投稿时间：2017-08-06 修订日期：2017-09-26 |
| DOI：10.3969/j.issn.1674-8085.2017.06.020 |
| 中文关键词: 布洛芬 阿司匹林哮喘(AIA) 白三烯(LTs) 非甾体抗炎药(NSAIDs) |
| 英文关键词: ibuprofen aspirin induced asthma (AIA) leukotriene (LTs) non-steroidal anti-inflammatory drugs (NSAIDs) |
| 基金项目: |
| 作者 | 单位 | | 王晓刚 | 南昌大学第一附属医院药学部, 江西, 南昌 330006 | | 李红 | 南昌大学第一附属医院药学部, 江西, 南昌 330006 | | 张连凤 | 南昌大学第一附属医院药学部, 江西, 南昌 330006 | | 万颖超 | 南昌大学第一附属医院药学部, 江西, 南昌 330006 | | 刘晓琼 | 南昌大学第一附属医院药学部, 江西, 南昌 330006 | | 欧阳爱军 | 南昌大学第一附属医院药学部, 江西, 南昌 330006 |
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| 中文摘要: |
| 目的 让临床医师、药师进一步认识阿司匹林哮喘（AIA），熟悉AIA的诊断方法、处理措施及发病机制。方法 介绍并分析1例布洛芬诱发危重AIA患者的病史资料。结果 患者服用布洛芬后突发AIA，立即转入呼吸ICU进行抢救，并采取相应的对症措施。其后患者AIA症状逐渐缓解，各项生命指标恢复正常，次日转入普通病房。结论 AIA目前尚无"金标准"诊断方法，主要依据患者AIA发生时间，病史，临床表现及动脉血气分析特点进行关联性评价。一旦发生AIA，应立即实施处理，尽快采取缓解气道阻塞，纠正低氧血症，恢复肺功能等对症措施。 |
| 英文摘要: |
| Objective:The purpose of this paper is to enable clinicians and pharmacists to further understand Aspirin Induced-Asthma (AIA) and be familiar with its diagnosis methods, treatment measures and pathogenesis. Methods:The history data of 1 case of severe AIA induced by ibuprofen was analyzed. Results:After taking ibuprofen, the patient burst into AIA, immediately was transferred to respiratory ICU for rescue, and took corresponding symptomatic measures. Subsequently, the patient's AIA symptoms gradually eased, the life indicators returned to normal. The patient was transferred to the general ward on the next day. Conclusion:There is no gold standard diagnostic method for AIA, which is mainly based on the time of AIA, history, clinical manifestation and the characteristics of arterial blood gas analysis. In the event of AIA, symptomatic measures such as relieving airway obstruction, correcting hypoxemia and restoring pulmonary function should be taken as soon as possible. |
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