| 戴一,贾晓益,王海菲.金铃子散抗炎有效部位筛选及质谱表征[J].井冈山大学自然版,2015,(1):103-106 |
| 金铃子散抗炎有效部位筛选及质谱表征 |
| ANTI-INFLAMMATORY ACTIVE FRACTION OF JINLINGZISAN AND ITS MS CHARACTERIZATION |
| 投稿时间：2014-08-17 修订日期：2014-12-12 |
| DOI：10.3969/j.issn.1674-8085.2015.01.022 |
| 中文关键词: 金铃子散 有效部位 抗炎 质谱 |
| 英文关键词: Jinlingzisan anti-inflammatory effective fraction MS |
| 基金项目:安徽省教育厅自然科学研究项目(KJ2012Z136) |
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| 中文摘要: |
| 目的 筛选金铃子散的抗炎有效部位并对有效部位进行质谱(MS)表征。方法 将金铃子散采用梯度极性溶剂石油醚、四氯化碳、三氯甲烷、乙酸乙酯、甲醇及水超声提取,提取物通过二甲苯致小鼠耳廓肿胀实验以确定抗炎有效部位,并对抗炎有效部位采用MS进行初步表征。结果 金铃子散石油醚提取物对小鼠耳廓肿胀有明显的抑制作用,MS分析其特征离子峰为m/z102.1、149.2、205.3、279.4、301.5、366.4。结论 金铃子散石油醚提取物具有明显的抗炎作用,为金铃子散的抗炎有效部位。 |
| 英文摘要: |
| Objective: To screen and characterize the anti-inflammatory effective fraction from Jinlingzisan. Methods: Jinlingzisan was ultrasonically extracted by petroleum ether, CCl4, CHCl3, ethyl acetate, methanol and water, respectively. The anti-inflammatory effective fraction was characterized by MS. Results: The petroleum ether extract of Jinlingzisan had the best anti-inflammatory effect and had ion peak of m/z 102.1, 149.2, 205.3, 279.4, 301.5 and 366.4. Conclusion: The effective fraction of anti-inflammatory from Jinlingzisan was petroleum ether extract. |
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