井冈山大学学报自然科学版

文章摘要

李伟,胡红梅.口腔幽门螺杆菌感染与慢性牙周炎相关性的系统评价[J].井冈山大学自然版,2013,(2):94-98

口腔幽门螺杆菌感染与慢性牙周炎相关性的系统评价

SYSTEM EVALUATION ON THE RELATIVITY BETWEEN ORAL HELICOBACTER PYLORI INFECTION AND PERIODONTAL DISEASE

DOI：

英文关键词: oral Helicobacter pylori periodontal disease system evaluation

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作者	单位
李伟,胡红梅

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中文摘要:

目的通过对口腔幽门螺杆菌感染与牙周病之间的关系进行系统评价。方法计算机检索MEDLINE、Pubmed、Highwire、CNKI，检索时间从1992～2011年，纳入所有研究口腔幽门螺杆菌感染与牙周病相关性的配对与非配对的病例对照研究。由2名评价者共同评价纳入研究质量，采用RevMan4．2软件对数据进行Meta分析，估计其OR值和95％CIo结果共纳入9个研究，纳入慢性牙周炎组研究例数共1698例，牙周健康组对照2226例，研究类型为随机对照实验或非随机对照实验，在总共9个研究中，都是以慢性牙周炎和非慢性牙周炎作为对照研究，结果表明慢性牙周炎组感染幽门螺杆菌的合并统计量的差别有统计学意义，统计结果表明，以牙周健康者为对照的研究其OR合并分别为1．66（95％CI1．43，1．91）。结论综合目前的研究，本次系统评价研究的结论说明口腔幽门螺杆菌感染是慢性牙周炎的一个危险因素。

英文摘要:

Objective： To systematically evaluate the relativity between oral Helicobacter pylori infection and periodontal disease because of present inconsistence. Methods： Case-control studies on relativity between oral H. pylori infection and Periodontal disease were collected by searching MEDLINE, Pubmed, Higheire, CNKI ranging from 1992 to 2011. The quality of included case studies was evaluated independently by two reviewers. RevMan 4.2 software was used to analyze and estimate its OR value and 95% CI. Results： 9 studies including 1698 patients with chronic periodontitis and 2226 patients with periodontal health were identified, research type is randomized controlled trials or non-randomized controlled trials, chronic periodontitis and periodontal health were set as case-control studies, the results showed that the combined statistics difference of chronic periodontitis group of H. pylori infection has statistic significance, statistical results indicate that the OR value is [ORcombined=1.66 （95% CI 1.43, 1.91） in the studies with periodontal healthy subjects as control. Conclusion： Based on the system evaluation research results, it could be concluded that oral H. pylori infection is a risk factor for chronic periodontitis.

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