| 夏志,汪清祥,彭勇,徐飞.支链氨基酸增强小鼠的游泳能力对其血氨和5-羟色胺变化的研究[J].井冈山大学自然版,2012,(2):90-93,103 |
| 支链氨基酸增强小鼠的游泳能力对其血氨和5-羟色胺变化的研究 |
| BRANCHED-CHAIN AMINO ACIDS SUPPLEMENTATION ENHANCES SWIMMING PERFORMANCE OF TRAINED MICE： EVIDENCE FROM CHANGES OF PLASMA AMMONIA AND SEROTONIN |
| |
| DOI： |
| 中文关键词: 支链氨基酸 小鼠 力竭游泳 5-羟色胺 血氨 |
| 英文关键词: branched chain amino acids （BCAAs） mice exhaustive swimming serotonin （5-HT） plasma ammonia （PA） |
| 基金项目:井冈山大学科研计划项目（JZ10035） |
|
| 摘要点击次数: 2520 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的探讨支链氨基酸（Branched-chain amino acids,BCAAs）对训练小鼠抗疲劳运动能力的影响。方法50只小鼠随机分为实验组（B1、B2、B3、B4）和对照组（C）。实验组分别灌胃补充BCAAs0.45、1.25、3.75和10g/kg.d,对照组灌胃生理盐水。各组小鼠5周递增负荷游泳训练后进行力竭游泳并取材。观察BCAAs对小鼠脑组织5-羟色胺（5-HT）、血氨（PA）和力竭游泳时间的影响。结果实验组小鼠血氨含量升高,脑组织匀浆中5-HT含量下降,但力竭运动游泳时间均显著延长。结果血氨浓度随剂量的增加而增大,C与B1组相比血氨水平无显著性差异,但明显低于B2、B3、B4组（P〈0.01）;C组小鼠5-羟色胺浓度显著高于实验组（P〈0.01）,实验组间随着补充剂量的增大5-羟色胺浓度减小;实验组小鼠力竭游泳能力明显强于对照组（P〈0.01）。实验组间,B2、B3组小鼠力竭时间明显长于B1组（分别为P〈0.05,P〈0.01）,B4组力竭时间与B1、B2、B3组相比则下降。结论BCAAs能够对抗运动性疲劳的发生发展,增强运动能力,但具有量效关系。 |
| 英文摘要: |
| Objective： To determine the effects of branched chain amino acids （BCAAs） on sport ability in trained mice. Methods： 50 KM mice were divided into experimental groups （group B1, B2, B3, B4） and control group （group C） randomly. The experimental groups respectively received BCAAs supplementation of0.15g/kg.d, 1.25g/kg.d, 3.75g/kg.d and 10g/kg.d by stomach intubations, and control group were fed with equivalent physiological saline solution. Effects of BCAAs on plasma ammonia （PA） and serotonin （5-HT） contents of mice brain tissue and the exhaustive swimming time were examined. Results： As for PA, the content increased along with the growing dosage of BCAAs supplementation, but there was no significant difference between group C and B1, but this significant difference existed when compared with B2, B3 and B4 （P 〈 0.01）. The concentration of 5-HT in group C were higher than experimental group （P 〈 0.01）, and decreased along with .the growing of BCAAs supplementation. The exhaustive swimming time of experimental groups were longer than control group （P 〈 0.01）. Compared within experimental groups, the exhaustive swimming time of mice for group B2 （P 〈 0.05） and B3 （P 〈 0.01） was longer than group B1 and was the shortest for group B4. Conclusion： BCAAs supplementation can counter against the onset and development of exercise-induced fatigue and sport ability, but the effect was dosage-dependent. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
